Hot spots in Topo protein drive shared autoimmune responses in scleroderma patients
Erika Darrah and Eleni Tiniakou identified “hot spots” in the Topo protein that are targeted by the immune system in scleroderma patients with different genetic backgrounds, which may help us understand why the immune system attacks healthy tissues in this autoimmune disease.
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Darrah Lab at EULAR 2020
Ashley Curran, a PhD student in our lab, gave an oral presentation at the virtual EULAR 2020 conference about her work elucidating the effect of citrullination on RA autoantigen processing and presentation.
Smoking is not to blame for PAD4 antibody development in patients with RA
Erika Darrah and colleagues in the Johns Hopkins Arthritis Center found that, although smoking is linked to the development of RA and specific immune responses to proteins in the body, smoking is not responsible for the development of immune responses to a related protein, PAD4. The study was featured on the Johns Hopkins Rheumatology website.
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Hopkins Rheumatology helps to #CUREMyositis
On Saturday, October 15, 2016, the Hopkins Rheumatology CARES (Centers Advancing RESearch) team was out in full force to support the “Myositis Run, Walk, n’ Roll 5k” event at Centennial Park in Columbia, MD.
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